An autoimmune disorder characterized by loss of melanocytes resulting in depigmented patches of skin and hair. Affects 0.5-2% of global population. Can be segmental (limited) or non-segmental (generalized). Associated with other autoimmune diseases.

• 1Clinical examination
• 2Wood's lamp examination
• 3Skin biopsy (rarely)
• 4Thyroid function tests
• 5Assessment for other autoimmune diseases

Chronic condition; unpredictable course. Some patients achieve repigmentation with treatment, especially facial lesions. Extensive disease more resistant. Emotional impact often significant. No cure currently.

• Sun protection
• Avoid trauma to skin
• Early treatment
• Stress management
• Screening for associated autoimmune conditions