DISEASE SCANNER

Global Incurable Diseases Tracker

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Autoimmune Disease

Vasculitis

HIGH SEVERITY

An inflammation of blood vessels that causes changes in vessel walls including thickening, weakening, narrowing, and scarring. Can affect arteries, veins, and capillaries. These changes restrict blood flow, resulting in organ and tissue damage. There are many forms affecting different vessel sizes and organs.

Global Affected

2.0M

Countries

17

Symptoms

Fever
Fatigue
Weight loss
Muscle and joint pain
Nerve problems (numbness, weakness)
Skin changes (rashes, ulcers)
Shortness of breath
Cough
Headaches
Vision problems
Abdominal pain
Bloody urine

Treatment Options

High-dose corticosteroids
Cyclophosphamide
Methotrexate
Azathioprine
Mycophenolate mofetil
Rituximab
Tocilizumab
Plasma exchange
IVIG

Risk Factors

1Family history
2Other autoimmune diseases
3Hepatitis B or C
4Age (varies by type)
5Sex (varies by type)

Diagnostic Methods

  • 1Blood tests (ESR, CRP, ANCA)
  • 2Urine tests
  • 3Imaging (angiography, CT, MRI)
  • 4Biopsy of affected tissue
  • 5Chest X-ray

Prognosis

Variable by type and severity. Many forms can be controlled with treatment but require long-term immunosuppression. Untreated vasculitis can be life-threatening. Relapses are common.

Prevention

  • No known prevention
  • Early detection and treatment
  • Avoiding hepatitis infection

Research Status

Treatment typically involves corticosteroids and immunosuppressive drugs. Biologic agents like rituximab are increasingly used. Prompt treatment is essential to prevent organ damage. Relapses are common and require ongoing monitoring.

Sources

  • https://www.mayoclinic.org/diseases-conditions/vasculitis/symptoms-causes/syc-20363440
  • https://www.ncbi.nlm.nih.gov/books
  • https://www.mayoclinic.org/diseases-conditions
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.