DISEASE SCANNER

Global Incurable Diseases Tracker

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Gynecologic Condition

Vaginal Yeast Infection (Vulvovaginal Candidiasis)

LOW SEVERITY

A common fungal infection affecting up to 75% of women at least once in their lifetime. Caused by Candida overgrowth, most commonly Candida albicans. Characterized by intense itching and thick, white discharge. Recurrent infections (≥4 per year) affect 5-8% of women and significantly impact quality of life.

Global Affected

135.0M

Countries

20

Symptoms

Intense vaginal itching
Thick white cottage cheese-like discharge
Vulvar redness and swelling
Burning sensation
Pain during intercourse
Burning during urination
Vaginal soreness
Rash on vaginal area

Treatment Options

Topical azole antifungals (clotrimazole, miconazole)
Oral fluconazole (single dose)
Extended fluconazole for recurrent infections
Boric acid suppositories for resistant cases
Nystatin cream
Vaginal suppositories
Maintenance therapy for recurrent cases

Risk Factors

1Antibiotic use
2Pregnancy
3Uncontrolled diabetes
4Immunosuppression
5Oral contraceptives or hormone therapy
6Tight-fitting or synthetic clothing
7Douching
8Obesity

Diagnostic Methods

  • 1Clinical presentation
  • 2Vaginal pH testing (normal in candidiasis)
  • 3Wet mount microscopy with KOH prep
  • 4Gram stain
  • 5Fungal culture for recurrent cases
  • 6DNA probe tests

Prognosis

Uncomplicated yeast infections respond to treatment in 80-90% of cases within 3-7 days. Recurrent infections affect 5-8% of women and require longer initial therapy (7-14 days) followed by maintenance therapy. Non-albicans species may be more resistant to standard treatment. Chronic or recurrent infections significantly impact sexual health and quality of life. Diabetes control reduces recurrence rates. Most women can self-diagnose and treat after initial medical confirmation.

Prevention

  • Avoiding unnecessary antibiotic use
  • Wearing cotton underwear
  • Avoiding tight-fitting clothing
  • Keeping vaginal area dry
  • Managing blood sugar if diabetic
  • Probiotic supplementation
  • Avoiding douching

Research Status

Over-the-counter azole antifungals effective for uncomplicated infections. Recurrent infections require longer therapy and maintenance regimens. Non-albicans Candida species show increasing resistance. Research on probiotics, immunotherapy, and alternative antifungal agents.

Sources

  • https://www.cdc.gov/fungal/diseases/candidiasis
  • https://www.mayoclinic.org/diseases-conditions/yeast-infection
  • https://www.acog.org/womens-health/faqs/vaginal-yeast-infections

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.