DISEASE SCANNER

Global Incurable Diseases Tracker

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Gynecologic Condition

Vaginal Atrophy (Genitourinary Syndrome of Menopause)

LOW SEVERITY

Thinning, drying, and inflammation of the vaginal walls due to decreased estrogen levels, typically occurring after menopause. Affects urinary and sexual function.

Global Affected

45.0M

Countries

15

Symptoms

Vaginal dryness
Vaginal burning or itching
Pain during intercourse (dyspareunia)
Vaginal discharge
Urinary urgency
Recurrent urinary tract infections
Light bleeding after intercourse

Treatment Options

Vaginal estrogen cream
Vaginal estrogen tablets
Vaginal estrogen ring (Estring)
Vaginal moisturizers (regular use)
Water-based lubricants
Ospemifene (oral SERM)
Prasterone (DHEA vaginal insert)
Fractional CO2 laser therapy

Risk Factors

1Menopause
2Surgical removal of ovaries
3Breastfeeding
4Certain medications (anti-estrogens)
5Chemotherapy or pelvic radiation
6Smoking
7Never giving birth vaginally

Diagnostic Methods

  • 1Pelvic examination
  • 2Vaginal pH testing (elevated >5)
  • 3Wet mount microscopy
  • 4Hormone level testing
  • 5Biopsy (if atypical findings)

Prognosis

Excellent with treatment. Symptoms improve in 80-90% of women within 3-4 weeks of vaginal estrogen. Moisturizers provide ongoing relief. Treatment can be continued long-term safely. Laser therapy provides 12+ months improvement. Quality of life and sexual function significantly improve. No cure without estrogen restoration.

Prevention

  • Regular sexual activity (promotes blood flow)
  • Smoking cessation
  • Vaginal moisturizers before symptoms severe
  • Hormone therapy consideration at menopause

Research Status

Vaginal estrogen therapy (creams, tablets, rings), vaginal moisturizers and lubricants, oral ospemifene (SERM), laser therapy (vaginal rejuvenation), and systemic hormone therapy.

Affected Countries

United StatesUnited KingdomCanadaAustraliaGermanyFranceItalySpainJapanBrazilMexicoIndiaChinaRussiaSouth Africa

Sources

  • https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2013/12/treatment-of-menopause-associated-vasomotor-symptoms
  • https://www.menopause.org/publications/clinical-care-recommendations
  • https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.