DISEASE SCANNER

Global Incurable Diseases Tracker

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Ophthalmologic Disease

Uveitis

HIGH SEVERITY

Inflammation of the uvea, the middle layer of the eye consisting of the iris, ciliary body, and choroid. Can be infectious or non-infectious. Serious condition that can lead to vision loss.

Global Affected

2.8M

Countries

19

Symptoms

Eye redness
Eye pain
Light sensitivity
Blurred vision
Dark floating spots
Decreased vision
Whitish area inside lower eyelid

Treatment Options

Corticosteroid eye drops
Periocular corticosteroid injections
Intraocular corticosteroid implants
Oral corticosteroids
Immunosuppressive agents
Biologics (adalimumab)
Cycloplegic drops
Antibiotics/antivirals (if infectious)

Risk Factors

1Autoimmune diseases
2Infections
3Trauma
4Certain cancers
5Smoking
6Genetic factors (HLA-B27)
7Age (20-50)

Diagnostic Methods

  • 1Slit-lamp examination
  • 2Dilated fundus exam
  • 3OCT
  • 4Fluorescein angiography
  • 5Laboratory tests
  • 6Chest X-ray (sarcoidosis)
  • 7Syphilis testing
  • 8TB testing

Prognosis

Variable. Early treatment crucial. Can cause cataracts, glaucoma, macular edema. Vision-threatening if untreated. Chronic/recurrent in many. Requires long-term monitoring.

Prevention

  • No specific prevention
  • Early treatment of symptoms
  • Regular follow-up
  • Treat underlying conditions
  • Smoking cessation

Research Status

Corticosteroids (topical, periocular, intraocular, oral, IV) main treatment. Immunosuppressants for severe/recalcitrant cases. Biologics (adalimumab, infliximab) for certain types. Cycloplegics for pain/ciliary spasm. Treat underlying cause. Prompt treatment prevents complications.

Affected Countries

United StatesUnited KingdomCanadaAustraliaGermanyFranceItalySpainJapanBrazilMexicoIndiaChinaRussiaSwedenNetherlandsNorwayFinlandDenmark

Sources

  • https://www.mayoclinic.org/diseases-conditions/uveitis
  • https://www.hematology.org/education/patients
  • https://www.ncbi.nlm.nih.gov/books
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.