DISEASE SCANNER

Global Incurable Diseases Tracker

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Cancer

Testicular Cancer

MODERATE

The most common solid tumor in young men (15-35 years). Two main types: germ cell tumors (seminoma and non-seminoma) and non-germ cell tumors. Highly curable even when metastatic. Associated with cryptorchidism and family history.

Global Affected

75.0K

Countries

18

Symptoms

Painless testicular mass
Testicular swelling
Heaviness in scrotum
Dull ache
Gynecomastia
Back pain (retroperitoneal nodes)
Cough/dyspnea (lung mets)

Treatment Options

Surgery
Chemotherapy
Radiation therapy
Immunotherapy
Targeted therapy
Hormone therapy
Stem cell transplant
Palliative care

Risk Factors

1Age
2Family history
3Genetic mutations
4Smoking
5Alcohol consumption
6Obesity
7Physical inactivity
8Environmental exposures
9Infections (HPV, HBV, HCV, H. pylori)

Diagnostic Methods

  • 1Biopsy
  • 2Imaging (CT, MRI, PET)
  • 3Tumor markers
  • 4Genetic testing
  • 5Endoscopy
  • 6Blood tests
  • 7Screening programs

Prognosis

Excellent prognosis overall - most curable solid tumor. Stage I: 5-year survival 99%. Stage II: 5-year survival 95-96%. Stage III: 5-year survival 70-80% depending on tumor markers. Seminoma has slightly better prognosis than non-seminoma. Cisplatin-based chemotherapy curative in 90% of advanced cases. Fertility may be affected by treatment. Surveillance appropriate for Stage I. Relapse after complete response rare (<5%). Long-term survivors may experience late effects of chemotherapy.

Prevention

  • Smoking cessation
  • Sun protection
  • Healthy diet
  • Regular exercise
  • Vaccination (HPV, HBV)
  • Screening programs
  • Limit alcohol
  • Maintain healthy weight

Research Status

Orchiectomy for diagnosis/treatment. Platinum-based chemotherapy (BEP) for metastatic disease. Retroperitoneal lymph node dissection. Radiation for seminoma. Survival >95% overall; 70-80% even with metastases. Excellent prognosis.

Sources

  • https://www.cancer.gov
  • https://www.who.int/cancer
  • https://www.cancer.org

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.