DISEASE SCANNER

Global Incurable Diseases Tracker

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Dermatologic Condition

Shingles (Herpes Zoster)

MODERATE

A viral infection causing a painful rash, caused by reactivation of the varicella-zoster virus (chickenpox). Characterized by a stripe of blisters on one side of the body. Risk increases with age.

Global Affected

100.0M

Countries

19

Symptoms

Pain, burning, numbness
Sensitivity to touch
Red rash
Fluid-filled blisters
Itching
Fever
Headache
Fatigue
Postherpetic neuralgia

Treatment Options

Antiviral medications (acyclovir, valacyclovir, famciclovir)
Pain medications
Gabapentin
Pregabalin
Tricyclic antidepressants
Topical capsaicin
Corticosteroids
Shingrix vaccine (prevention)

Risk Factors

1Age (over 50)
2Weakened immune system
3Stress
4Chickenpox history
5Cancer
6HIV/AIDS
7Immunosuppressive medications

Diagnostic Methods

  • 1Visual examination
  • 2Viral culture
  • 3PCR testing
  • 4Tzanck smear
  • 5Physical examination

Prognosis

Usually resolves in 3-5 weeks. Postherpetic neuralgia can persist months to years. Vaccination prevents most cases. Early antiviral treatment crucial. Complications more common in elderly and immunocompromised.

Prevention

  • Shingrix vaccine (recommended age 50+)
  • Early treatment of symptoms
  • Avoid contact with immunocompromised and pregnant women
  • Chickenpox vaccine (prevents initial infection)

Research Status

Antivirals (acyclovir, valacyclovir) within 72 hours reduce severity. Shingrix vaccine highly effective for prevention (>90%). Gabapentinoids and TCAs for postherpetic neuralgia. Early treatment prevents complications.

Sources

  • https://www.cdc.gov/shingles
  • https://www.mayoclinic.org/diseases-conditions/shingles
  • https://www.hematology.org/education/patients
  • https://www.ncbi.nlm.nih.gov/books
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.