DISEASE SCANNER
Global Incurable Diseases Tracker
Pulmonary Sarcoidosis
A multisystem inflammatory disease characterized by formation of non-caseating granulomas, most commonly affecting the lungs and lymph nodes. Of unknown cause, thought to involve abnormal immune response to environmental triggers in genetically susceptible individuals.
2.0M
20
Symptoms
Treatment Options
Risk Factors
Diagnostic Methods
- 1Chest X-ray (bilateral hilar lymphadenopathy)
- 2High-resolution CT
- 3PET scan
- 4Tissue biopsy (non-caseating granulomas)
- 5Pulmonary function tests
- 6Serum ACE level
- 7Calcium levels
Prognosis
Variable; 60% have spontaneous remission. 10-30% develop chronic disease. 5% progress to pulmonary fibrosis. Higher morbidity in African Americans. Overall 1-5% mortality.
Prevention
- No known prevention
- Avoid potential environmental triggers
- Regular monitoring for progression
Research Status
Often resolves spontaneously without treatment. Corticosteroids for symptomatic or progressive disease. Immunosuppressants for steroid-resistant cases. TNF inhibitors for refractory disease.
Affected Countries
Sources
- https://www.lung.org/lung-health-diseases/lung-disease-lookup/sarcoidosis
- https://www.hematology.org/education/patients
- https://www.ncbi.nlm.nih.gov/books
- https://rarediseases.org/rare-diseases
Medical Disclaimer
This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.