DISEASE SCANNER
Global Incurable Diseases Tracker
Restless Legs Syndrome
A neurological disorder causing uncomfortable sensations in the legs and an irresistible urge to move them. Symptoms worse at rest and in the evening/night. Significantly disrupts sleep. Associated with iron deficiency, kidney disease, pregnancy, and certain medications.
150.0M
89
Symptoms
Treatment Options
Risk Factors
Diagnostic Methods
- 1Clinical diagnosis (URGE criteria)
- 2Serum ferritin
- 3Iron studies
- 4Polysomnography (if OSA suspected)
- 5Sleep diary
- 6International RLS Rating Scale
Prognosis
Chronic condition, often progressive. Symptoms fluctuate. Good response to treatment but augmentation can occur with dopamine agonists. Quality of life improves with therapy.
Prevention
- Maintain iron stores
- Regular exercise
- Avoid caffeine/alcohol
- Good sleep hygiene
- Review medications
- Treat underlying conditions
Research Status
Iron supplementation if deficient. Dopaminergic agents (ropinirole, pramipexole) first-line. Alpha-2-delta ligands (gabapentin, pregabalin) increasingly preferred. Opioids for refractory cases. Treat underlying causes.
Affected Countries
Sources
- https://www.mayoclinic.org/diseases-conditions/restless-legs-syndrome
- https://www.ncbi.nlm.nih.gov/books
- https://www.mayoclinic.org/diseases-conditions
- https://rarediseases.org/rare-diseases
Medical Disclaimer
This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.