DISEASE SCANNER

Global Incurable Diseases Tracker

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Autoimmune Disease

Psoriasis

LOW SEVERITY

A chronic autoimmune skin condition causing rapid skin cell turnover, resulting in thick, scaly plaques. Associated with psoriatic arthritis in 30% of patients and increased cardiovascular risk. Strong genetic component with environmental triggers.

Global Affected

125.0M

Countries

15

Symptoms

Red patches with silvery scales
Dry, cracked skin
Itching, burning, soreness
Thickened, pitted nails
Swollen joints (psoriatic arthritis)
Koebner phenomenon

Treatment Options

Corticosteroids
Immunosuppressants
Biologic agents
DMARDs
Plasmapheresis
IVIG
Physical therapy
Symptom management

Risk Factors

1Female gender
2Family history
3Genetic predisposition
4Environmental triggers
5Infections
6Hormonal factors
7Smoking

Diagnostic Methods

  • 1Autoantibody testing
  • 2Inflammatory markers
  • 3Imaging
  • 4Biopsy
  • 5Clinical criteria
  • 6Exclusion of other causes

Prognosis

Variable; many autoimmune diseases are chronic with relapsing-remitting courses. Early treatment and modern biologics have significantly improved outcomes.

Prevention

  • No specific prevention
  • Smoking cessation
  • Avoidance of triggers
  • Early diagnosis and treatment
  • Regular monitoring

Research Status

IL-17 inhibitors (secukinumab, ixekizumab, bimekizumab) and IL-23 inhibitors (guselkumab, risankizumab, tildrakizumab) highly effective. Topical treatments and phototherapy for mild disease.

Affected Countries

AustraliaBrazilCanadaChinaGermanyEESpainFranceUnited KingdomIndiaIcelandItalyJapanSloveniaUnited States

Sources

  • https://www.ncbi.nlm.nih.gov/books/NBK519046
  • https://www.ncbi.nlm.nih.gov/books
  • https://www.mayoclinic.org/diseases-conditions
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.