DISEASE SCANNER

Global Incurable Diseases Tracker

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Autoimmune Disease

Polymyalgia Rheumatica

MODERATE

An inflammatory disorder causing muscle pain and stiffness, especially in the shoulders, neck, and hips. Symptoms are typically worse in the morning. Usually develops quickly, often overnight. Closely related to giant cell arteritis and can occur together. Almost exclusively affects adults over 50.

Global Affected

900.0K

Countries

17

Symptoms

Aches and pain in shoulders
Aches and pain in neck
Aches and pain in hips
Morning stiffness lasting >45 minutes
Fatigue
Mild fever
Unintentional weight loss
Depression
Limited range of motion

Treatment Options

Low-dose corticosteroids (prednisone)
Methotrexate (steroid-sparing)
Tocilizumab
Physical therapy
Calcium and vitamin D supplementation
Bone protection (bisphosphonates)

Risk Factors

1Age over 50
2Female sex
3Northern European ancestry

Diagnostic Methods

  • 1Blood tests (ESR, CRP elevated)
  • 2Physical examination
  • 3Response to corticosteroid trial
  • 4Imaging (ultrasound, MRI)
  • 5Tests to rule out other conditions

Prognosis

Excellent; most patients respond well to treatment and recover fully within 2 years. Relapses occur in 30-50% when tapering steroids. No joint damage occurs despite symptoms.

Prevention

  • No known prevention
  • Regular exercise
  • Healthy diet

Research Status

Responds dramatically to low-dose corticosteroids, often within 24-48 hours. Treatment typically continues for 1-2 years with gradual tapering. Regular monitoring for giant cell arteritis symptoms is essential. Physical therapy helps maintain mobility.

Sources

  • https://www.mayoclinic.org/diseases-conditions/polymyalgia-rheumatica/symptoms-causes/syc-20376539
  • https://www.ncbi.nlm.nih.gov/books
  • https://www.mayoclinic.org/diseases-conditions
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.