DISEASE SCANNER
Global Incurable Diseases Tracker
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Endocrine Disorder
Pheochromocytoma
HIGH SEVERITY
A rare tumor of the adrenal medulla that produces excess catecholamines (epinephrine and norepinephrine), causing episodic or persistent hypertension and other symptoms. Usually benign but can be malignant.
Global Affected
200.0K
Countries
15
Symptoms
Episodic hypertension
Severe headaches
Sweating
Palpitations
Anxiety/panic attacks
Tremor
Chest pain
Pallor
Treatment Options
Hormone replacement
Hormone suppression
Medications
Surgery
Radiation therapy
Lifestyle modifications
Regular monitoring
Risk Factors
1Family history
2Autoimmune disease
3Age
4Obesity
5Genetic mutations
6Iodine deficiency/excess
7Medications
8Pituitary tumors
Diagnostic Methods
- 1Hormone level testing
- 2Imaging (CT, MRI, ultrasound)
- 3Stimulation/suppression tests
- 4Autoantibody testing
- 5Genetic testing
Prognosis
Generally excellent with proper hormone replacement or suppression. Lifelong monitoring typically required. Complications preventable with good control.
Prevention
- Screening for at-risk individuals
- Iodine sufficiency
- Avoidance of trigger medications
- Genetic counseling
- Lifestyle modifications
Research Status
Surgical resection after alpha-blockade (phenoxybenzamine). Laparoscopic adrenalectomy standard. Genetic testing for hereditary forms (MEN2, VHL, NF1). MIBG and FDG-PET for metastatic disease.
Affected Countries
Sources
- https://www.endocrine.org
- https://www.ncbi.nlm.nih.gov/books/NBK278949
- https://www.hematology.org/education/patients
- https://www.ncbi.nlm.nih.gov/books
- https://rarediseases.org/rare-diseases
Medical Disclaimer
This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.