DISEASE SCANNER

Global Incurable Diseases Tracker

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Infectious Disease

Nipah Virus Infection

HIGH SEVERITY

A zoonotic virus transmitted from animals (fruit bats, pigs) to humans, with potential for person-to-person spread. Causes severe respiratory illness and encephalitis. First identified in Malaysia in 1998. Case fatality rate 40-75%. Outbreaks in Southeast Asia, primarily Bangladesh and India.

Global Affected

50.0K

Countries

15

Symptoms

Fever
Headache
Cough
Sore throat
Difficulty breathing
Vomiting
Severe respiratory distress
Encephalitis
Seizures
Coma
Personality changes
Brain swelling
Long-term neurological deficits

Treatment Options

Supportive care
Mechanical ventilation
Treatment of encephalitis
Anticonvulsants
Ribavirin (possibly beneficial)
Monoclonal antibody m102.4 (compassionate use)
Intensive care
Rehabilitation (survivors)

Risk Factors

1Contact with fruit bats
2Contact with pigs
3Drinking raw date palm sap
4Eating fruits contaminated by bats
5Close contact with infected patients
6Healthcare worker exposure
7Living in outbreak areas
8Bushmeat consumption

Diagnostic Methods

  • 1RT-PCR
  • 2Serological tests (IgM, IgG)
  • 3Viral isolation
  • 4Immunohistochemistry
  • 5Clinical evaluation
  • 6Epidemiological link
  • 7Cerebrospinal fluid analysis

Prognosis

Poor. Case fatality rate 40-75%. Survivors may have persistent neurological deficits including personality changes, seizures. Relapse encephalitis can occur months later. Permanent brain damage possible. Recovery incomplete in many survivors.

Prevention

  • Avoid contact with fruit bats
  • Avoid contact with pigs
  • Avoid raw date palm sap
  • Wash fruits thoroughly
  • Personal protective equipment
  • Isolation of patients
  • Contact tracing
  • Surveillance systems
  • Health education

Research Status

No specific treatment or vaccine approved. Supportive care only. Monoclonal antibody (m102.4) available on compassionate use. Ribavirin may have some benefit. Infection control crucial. Surveillance and rapid response. Research into vaccines ongoing.

Sources

  • https://www.who.int/health-topics/nipah-virus-infection
  • https://www.cdc.gov/vhf/nipah
  • https://www.mayoclinic.org/diseases-conditions/nipah-virus

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.