DISEASE SCANNER
Global Incurable Diseases Tracker
Narcolepsy Type 1
A chronic neurological disorder affecting the brain's ability to control sleep-wake cycles. Characterized by excessive daytime sleepiness and cataplexy (sudden muscle weakness triggered by emotions). Often caused by loss of hypocretin-producing neurons. Onset typically in adolescence.
3.0M
89
Symptoms
Treatment Options
Risk Factors
Diagnostic Methods
- 1Polysomnography
- 2Multiple Sleep Latency Test (MSLT)
- 3HLA typing
- 4CSF hypocretin-1 level
- 5Epworth Sleepiness Scale
- 6Actigraphy
Prognosis
Lifelong condition with no cure. Symptoms controllable with medication. Quality of life can be good with proper management. Safety concerns (driving, machinery). Higher risk of accidents.
Prevention
- No primary prevention
- Early diagnosis
- Genetic counseling (limited)
- Avoidance of sleep deprivation
- Stress management
Research Status
Wake-promoting agents (modafinil, armodafinil). Sodium oxybate for cataplexy and nighttime sleep. Stimulants (methylphenidate). Antidepressants for cataplexy. Scheduled naps help. Orexin/hypocretin agonists in development.
Affected Countries
Sources
- https://www.mayoclinic.org/diseases-conditions/narcolepsy
- https://www.ncbi.nlm.nih.gov/books
- https://www.mayoclinic.org/diseases-conditions
- https://rarediseases.org/rare-diseases
Medical Disclaimer
This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.