DISEASE SCANNER

Global Incurable Diseases Tracker

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Metabolic Disorder

Metabolic Syndrome

MODERATE

A cluster of conditions including increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels. Occurring together, they increase risk of heart disease, stroke, and type 2 diabetes. Very common in developed countries.

Global Affected

1.0B

Countries

89

Symptoms

Large waist circumference
High blood pressure
High blood sugar
High triglycerides
Low HDL cholesterol
Fatigue
Blurred vision (if diabetic)
Increased thirst

Treatment Options

Weight loss program
Exercise (150 min/week)
Mediterranean diet
Blood pressure medications
Statins
Metformin
GLP-1 agonists
Bariatric surgery
Smoking cessation

Risk Factors

1Obesity (especially abdominal)
2Physical inactivity
3Insulin resistance
4Age >50
5Family history of diabetes
6Polycystic ovary syndrome
7Sleep apnea
8Hispanic/Latino ethnicity
9Smoking

Diagnostic Methods

  • 1Waist circumference
  • 2Blood pressure measurement
  • 3Fasting glucose
  • 4HbA1c
  • 5Lipid panel
  • 6Insulin levels
  • 7HOMA-IR calculation

Prognosis

Good with lifestyle changes. 5-fold increased cardiovascular risk. 2-fold increased diabetes risk. Reversible with effective intervention. Major public health concern due to prevalence.

Prevention

  • Maintain healthy weight
  • Regular physical activity
  • Healthy diet
  • Avoid sugary beverages
  • Limit processed foods
  • Regular health screenings
  • Stress management

Research Status

Lifestyle modification is cornerstone: weight loss, exercise, healthy diet. Medications for individual components (BP, lipids, glucose). Metformin for prediabetes. Bariatric surgery for obese. Intensive lifestyle intervention can reverse metabolic syndrome.

Sources

  • https://www.mayoclinic.org/diseases-conditions/metabolic-syndrome
  • https://www.heart.org/en/health-topics/metabolic-syndrome
  • https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/prediabetes-insulin-resistance

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.