DISEASE SCANNER

Global Incurable Diseases Tracker

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Dermatologic Condition

Lichen Planus

MODERATE

An inflammatory condition affecting skin, hair, nails, and mucous membranes. Characterized by purplish, itchy, flat-topped bumps. Oral lichen planus affects mucous membranes. Can be triggered by hepatitis C, certain medications, or flu vaccine.

Global Affected

1.0M

Countries

15

Symptoms

Purplish, flat-topped bumps
Itching
Lacy white patches in mouth
Painful oral ulcers
Hair loss
Nail damage or loss
Genital lesions
Skin eruptions at injury sites

Treatment Options

Topical corticosteroids
Topical calcineurin inhibitors
Oral antihistamines (for itching)
Oral corticosteroids
Phototherapy (PUVA)
Retinoids
Tacrolimus ointment
Cyclosporine (severe cases)
Mouthwashes (oral form)
Treat underlying hepatitis C

Risk Factors

1Middle age
2Hepatitis C infection
3Certain medications (NSAIDs, antimalarials)
4Family history
5Stress
6Genetic factors
7Autoimmune associations

Diagnostic Methods

  • 1Physical examination
  • 2Biopsy of skin or mucous membrane
  • 3Hepatitis C testing
  • 4Differential diagnosis (lichenoid drug eruption)
  • 5Patch testing (if suspected allergic)

Prognosis

Usually self-limiting within 1-2 years, but can be chronic. Oral and nail forms more persistent. Small risk of oral cancer with mucosal forms requiring monitoring. Cutaneous forms may leave hyperpigmentation.

Prevention

  • Screen for hepatitis C
  • Avoid triggering medications if possible
  • Stress management
  • Regular dental/oral exams (oral form)
  • Sun protection
  • Avoid trauma to skin

Research Status

Topical corticosteroids first-line. Oral corticosteroids for severe cases. Phototherapy effective for widespread disease. Treat underlying hepatitis C if present. Regular monitoring for oral cancer in mucosal forms.

Affected Countries

AustraliaBrazilCanadaChinaCzech RepublicGermanySpainFranceUnited KingdomIndonesiaIndiaItalyJapanThailandUnited States

Sources

  • https://www.mayoclinic.org/diseases-conditions/lichen-planus
  • https://www.hematology.org/education/patients
  • https://www.ncbi.nlm.nih.gov/books
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.