DISEASE SCANNER

Global Incurable Diseases Tracker

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Nephrologic Disease

Kidney Stones (Nephrolithiasis)

MODERATE

Hard deposits of minerals and salts that form inside the kidneys. Can affect any part of the urinary tract. Cause severe pain when passing. Very common, affecting 1 in 11 people. Often recurrent. Types include calcium oxalate, uric acid, struvite, and cystine stones.

Global Affected

50.0M

Countries

22

Symptoms

Severe flank pain (renal colic)
Pain radiating to groin
Blood in urine
Nausea/vomiting
Frequent urination
Burning during urination
Cloudy/foul-smelling urine
Fever (if infection)
Urinary urgency

Treatment Options

Pain relievers (NSAIDs)
Hydration
Alpha-blockers (medical expulsive)
Extracorporeal shock wave lithotripsy (ESWL)
Ureteroscopy
Percutaneous nephrolithotomy
Open surgery (rare)
Thiazide diuretics (prevention)
Dietary modifications

Risk Factors

1Low fluid intake
2High sodium diet
3High oxalate diet
4Family history
5Obesity
6High protein diet
7Inflammatory bowel disease
8Gout
9Urinary tract infections
10Certain medications

Diagnostic Methods

  • 1CT scan (non-contrast - gold standard)
  • 2Ultrasound
  • 3X-ray (KUB)
  • 4Urinalysis
  • 5Blood tests (kidney function)
  • 6Stone analysis
  • 724-hour urine collection

Prognosis

Excellent. Most stones pass spontaneously. Recurrence common (50% within 5-10 years). Preventable with dietary changes and hydration. Rarely causes permanent kidney damage. Quality of life good with prevention.

Prevention

  • Drink 2-3 liters water daily
  • Limit sodium intake
  • Moderate protein intake
  • Limit oxalate-rich foods
  • Maintain healthy weight
  • Calcium with meals (binds oxalate)
  • Citrate supplements
  • Regular follow-up

Research Status

Most pass spontaneously with hydration and pain control. Lithotripsy for larger stones. Ureteroscopy and percutaneous nephrolithotomy for complex cases. Prevention through diet and hydration. Research on medication dissolution and improved procedures ongoing.

Sources

  • https://www.niddk.nih.gov/health-information/urologic-diseases/kidney-stones
  • https://www.mayoclinic.org/diseases-conditions/kidney-stones
  • https://www.kidney.org/atoz/content/kidneystones

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.