DISEASE SCANNER

Global Incurable Diseases Tracker

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Endocrine Disorder

Hypothyroidism (Underactive Thyroid)

MODERATE

A condition where the thyroid gland doesn't produce enough thyroid hormones. Slows down many of the body's functions. Hashimoto's thyroiditis is the most common cause in developed countries. Can occur at any age but is more common in older women.

Global Affected

200.0M

Countries

138

Symptoms

Fatigue
Increased sensitivity to cold
Constipation
Dry skin
Weight gain
Puffy face
Hoarse voice
Coarse hair and hair loss
Muscle weakness
Muscle aches, tenderness and stiffness
Pain, stiffness or swelling in joints
Heavy or irregular menstrual periods
Depression
Impaired memory
Slowed heart rate

Treatment Options

Hormone replacement
Hormone suppression
Medications
Surgery
Radiation therapy
Lifestyle modifications
Regular monitoring

Risk Factors

1Family history
2Autoimmune disease
3Age
4Obesity
5Genetic mutations
6Iodine deficiency/excess
7Medications
8Pituitary tumors

Diagnostic Methods

  • 1Hormone level testing
  • 2Imaging (CT, MRI, ultrasound)
  • 3Stimulation/suppression tests
  • 4Autoantibody testing
  • 5Genetic testing

Prognosis

Generally excellent with proper hormone replacement or suppression. Lifelong monitoring typically required. Complications preventable with good control.

Prevention

  • Screening for at-risk individuals
  • Iodine sufficiency
  • Avoidance of trigger medications
  • Genetic counseling
  • Lifestyle modifications

Research Status

Daily oral levothyroxine (synthetic T4 hormone). Dosage based on TSH levels, adjusted every 6-8 weeks until stable. Lifelong treatment usually required. Regular monitoring of thyroid function. Excellent prognosis with treatment.

Sources

  • https://www.endocrine.org
  • https://www.ncbi.nlm.nih.gov/books/NBK278949
  • https://www.hematology.org/education/patients
  • https://www.ncbi.nlm.nih.gov/books
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.