DISEASE SCANNER

Global Incurable Diseases Tracker

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Dermatologic Condition

Hidradenitis Suppurativa (Acne Inversa)

HIGH SEVERITY

A chronic inflammatory skin condition affecting apocrine gland-bearing areas (armpits, groin, under breasts, buttocks). Characterized by painful nodules, abscesses, sinus tracts, and scarring. Significantly impacts quality of life. Three stages (Hurley) based on severity.

Global Affected

4.0M

Countries

15

Symptoms

Painful pea-sized lumps
Tunnels under skin (sinus tracts)
Blackheads in pairs
Scarring and keloids
Foul-smelling drainage
Itching and burning
Restricted movement from scarring

Treatment Options

Topical antibiotics (clindamycin)
Oral antibiotics (tetracyclines)
Corticosteroid injections
Biologics (adalimumab, infliximab)
Hormonal therapy
Metformin (if insulin resistant)
Zinc supplements
Wide local excision
Deroofing procedure
Laser therapy
Lifestyle modifications

Risk Factors

1Family history
2Obesity
3Female gender
4Smoking
5Hormonal factors
6Metabolic syndrome
7Crohn's disease association
8Genetic predisposition

Diagnostic Methods

  • 1Clinical diagnosis
  • 2Physical examination
  • 3Assessment of Hurley stage
  • 4Cultures (to rule out infection)
  • 5Biopsy (rarely)
  • 6Assessment of comorbidities

Prognosis

Chronic relapsing condition with no cure. Early aggressive treatment prevents progression. Recurrence common after surgery. Significant impact on quality of life. Associated with depression and social isolation.

Prevention

  • Weight management
  • Smoking cessation
  • Loose-fitting clothing
  • Avoid shaving affected areas
  • Antibacterial washes
  • Early treatment of flares
  • Regular exercise (loose clothing)
  • Anti-inflammatory diet (possible benefit)

Research Status

Adalimumab first FDA-approved biologic. Other TNF inhibitors and IL-17 inhibitors showing efficacy. Wide excisional surgery for severe cases. Laser hair removal adjunctive. Research into anti-inflammatory diet impact.

Affected Countries

AustraliaBrazilCanadaChileChinaGermanySpainFranceUnited KingdomItalyJapanMexicoPortugalUkraineUnited States

Sources

  • https://www.mayoclinic.org/diseases-conditions/hidradenitis-suppurativa
  • https://www.hematology.org/education/patients
  • https://www.ncbi.nlm.nih.gov/books
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.