DISEASE SCANNER
Global Incurable Diseases Tracker
Hepatoblastoma
The most common malignant liver tumor in children, usually occurring before age 3. Associated with prematurity, low birth weight, and Beckwith-Wiedemann syndrome. Rising incidence correlates with improved survival of premature infants.
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Symptoms
Treatment Options
Risk Factors
Diagnostic Methods
- 1Biopsy
- 2Imaging (CT, MRI, PET)
- 3Tumor markers
- 4Genetic testing
- 5Endoscopy
- 6Blood tests
- 7Screening programs
Prognosis
Complete surgical resection offers 80-90% long-term survival. Pretreatment extent of disease (PRETEXT) staging predicts outcome. PRETEXT I-II has >90% survival; PRETEXT IV has 60-70%. Metastatic disease at diagnosis has 40-60% survival with intensified therapy. Cisplatin-based chemotherapy is backbone of treatment. Liver transplant for unresectable tumors offers 70-80% survival. AFP levels track treatment response. Survivors need monitoring for late effects.
Prevention
- Smoking cessation
- Sun protection
- Healthy diet
- Regular exercise
- Vaccination (HPV, HBV)
- Screening programs
- Limit alcohol
- Maintain healthy weight
Research Status
Surgical resection (often after neoadjuvant chemotherapy). Cisplatin-based chemotherapy. Liver transplant for unresectable tumors. Survival 80-90% with complete resection. Liver-directed therapies for recurrences.
Affected Countries
Sources
- https://www.cancer.gov
- https://www.who.int/cancer
- https://www.cancer.org
Medical Disclaimer
This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.