DISEASE SCANNER

Global Incurable Diseases Tracker

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Autoimmune Disease

Hashimoto's Thyroiditis

LOW SEVERITY

The most common cause of hypothyroidism in iodine-sufficient regions. An autoimmune disorder where antibodies (anti-TPO, anti-thyroglobulin) attack the thyroid gland. Strongly associated with other autoimmune diseases. More common in women (5-10:1).

Global Affected

14.0M

Countries

15

Symptoms

Fatigue
Weight gain
Cold intolerance
Constipation
Dry skin
Hair loss
Depression
Goiter

Treatment Options

Corticosteroids
Immunosuppressants
Biologic agents
DMARDs
Plasmapheresis
IVIG
Physical therapy
Symptom management

Risk Factors

1Female gender
2Family history
3Genetic predisposition
4Environmental triggers
5Infections
6Hormonal factors
7Smoking

Diagnostic Methods

  • 1Autoantibody testing
  • 2Inflammatory markers
  • 3Imaging
  • 4Biopsy
  • 5Clinical criteria
  • 6Exclusion of other causes

Prognosis

Variable; many autoimmune diseases are chronic with relapsing-remitting courses. Early treatment and modern biologics have significantly improved outcomes.

Prevention

  • No specific prevention
  • Smoking cessation
  • Avoidance of triggers
  • Early diagnosis and treatment
  • Regular monitoring

Research Status

Levothyroxine replacement therapy highly effective. Combination T4/T3 therapy controversial. Selenium supplementation may reduce antibodies. No curative treatment; lifelong therapy required.

Affected Countries

AustraliaBrazilCanadaChinaCzech RepublicGermanySpainFranceUnited KingdomIndiaItalyJapanThailandUnited StatesSouth Africa

Sources

  • https://www.ncbi.nlm.nih.gov/books/NBK519046
  • https://www.ncbi.nlm.nih.gov/books
  • https://www.mayoclinic.org/diseases-conditions
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.