DISEASE SCANNER
Global Incurable Diseases Tracker
Generalized Anxiety Disorder (GAD)
A chronic mental health condition characterized by persistent, excessive, and uncontrollable worry about everyday situations and events. Affects 3-6% of adults worldwide, with women affected twice as often as men. Causes significant impairment in social, occupational, and other important areas of functioning.
273.0M
20
Symptoms
Treatment Options
Risk Factors
Diagnostic Methods
- 1Clinical interview per DSM-5 criteria
- 2GAD-7 screening questionnaire
- 3HAM-A (Hamilton Anxiety Rating Scale)
- 4Medical evaluation to rule out physical causes
- 5Thyroid function tests
- 6Assessment of functional impairment
Prognosis
With appropriate treatment, 50-60% of patients achieve remission. CBT provides sustained benefits with 50-60% response rates. SSRIs effective in 50-70% of cases. Relapse common if treatment discontinued prematurely (30-50% within 6 months). Chronic course with waxing and waning symptoms in 40-50% of patients. Comorbid depression worsens prognosis. Early intervention improves long-term outcomes. Combination therapy (medication + CBT) most effective for severe cases.
Prevention
- Stress management techniques
- Regular exercise
- Adequate sleep hygiene
- Limiting caffeine and alcohol
- Early intervention for anxiety symptoms
- Building social support networks
- Mindfulness and relaxation practices
Research Status
Cognitive-behavioral therapy (CBT) and SSRIs/SNRIs are first-line treatments with comparable efficacy. Mindfulness-based interventions show promise. Research on neurobiological mechanisms, genetic factors, and personalized treatment approaches including pharmacogenomics.
Affected Countries
Sources
- https://www.mayoclinic.org/diseases-conditions/generalized-anxiety-disorder
- https://www.who.int/news-room/fact-sheets/detail/anxiety-disorders
- https://www.hematology.org/education/patients
- https://www.ncbi.nlm.nih.gov/books
- https://rarediseases.org/rare-diseases
Medical Disclaimer
This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.