DISEASE SCANNER
Global Incurable Diseases Tracker
Nonalcoholic Fatty Liver Disease (NAFLD)
A condition in which excess fat builds up in the liver, not due to alcohol use. The most common chronic liver disease worldwide, affecting 25% of the global population. Ranges from simple steatosis to nonalcoholic steatohepatitis (NASH) which can progress to cirrhosis.
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Symptoms
Treatment Options
Risk Factors
Diagnostic Methods
- 1Liver function tests
- 2Imaging (ultrasound, CT, MRI)
- 3Liver biopsy
- 4FibroScan
- 5Viral serologies
- 6Autoantibody testing
Prognosis
Variable; depends on etiology and stage at diagnosis. Early intervention can prevent progression. Some conditions are curable.
Prevention
- Hepatitis vaccination
- Moderate alcohol consumption
- Healthy weight
- Avoid hepatotoxins
- Regular screening
- Early treatment
Research Status
Weight loss (7-10% body weight). Mediterranean diet. Exercise (150 min/week). Management of diabetes, lipids, hypertension. Vitamin E (for NASH without diabetes). Avoid alcohol. Resmetirom approved 2024. Liver transplant for end-stage disease.
Affected Countries
Sources
- https://www.liverfoundation.org
- https://www.niddk.nih.gov/health-information/liver-disease
- https://www.hematology.org/education/patients
- https://www.ncbi.nlm.nih.gov/books
- https://rarediseases.org/rare-diseases
Medical Disclaimer
This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.