DISEASE SCANNER

Global Incurable Diseases Tracker

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Infectious Disease

Ebola Virus Disease

HIGH SEVERITY

A rare but severe, often fatal hemorrhagic fever caused by Ebola virus. Zoonotic disease transmitted from wild animals to humans, then human-to-human. Case fatality rate 25-90% depending on outbreak. West Africa 2014-2016 outbreak: 28,000+ cases.

Global Affected

35.0K

Countries

35

Symptoms

Fever
Fatigue
Muscle pain
Headache
Sore throat
Vomiting
Diarrhea
Rash
Impaired kidney/liver function
Hemorrhage (internal/external)

Treatment Options

Inmazeb (atoltivimab/maftivimab/odesivimab)
Ebanga (ansuvimab-zykl)
Supportive care
IV fluids and electrolytes
Oxygen therapy
Treatment of secondary infections

Risk Factors

1Contact with infected bodily fluids
2Healthcare worker in outbreak area
3Bushmeat handling
4Caring for Ebola patients
5Traditional burial practices
6Travel to endemic regions

Diagnostic Methods

  • 1RT-PCR
  • 2ELISA antigen detection
  • 3IgM/IgG serology
  • 4Virus isolation
  • 5Immunohistochemistry
  • 6Point-of-care rapid diagnostic tests

Prognosis

Case fatality rate 25-90% depending on outbreak. With early supportive care and new antibody treatments: mortality reduced to ~10-30%.

Prevention

  • Ervebo vaccine for high-risk populations
  • Infection control measures
  • Safe burial practices
  • Contact tracing
  • Quarantine protocols
  • Personal protective equipment

Research Status

Two monoclonal antibody treatments approved: Inmazeb and Ebanga. Ervebo vaccine (rVSV-ZEBOV) FDA-approved. Research into broad-spectrum filovirus vaccines and therapies. Improved supportive care reducing mortality.

Affected Countries

GNLRSLDR CongoCGGAGQUgandaKenyaRWBITanzaniaZambiaZimbabweBWNASouth AfricaEthiopiaSOMaliNigeriaSenegalCIGhanaBFNETDSSSudanERDJCFCMGQST

Sources

  • https://www.cdc.gov
  • https://www.who.int
  • https://www.hematology.org/education/patients
  • https://www.ncbi.nlm.nih.gov/books
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.