DISEASE SCANNER

Global Incurable Diseases Tracker

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Chronic Condition

Long COVID (Post-Acute Sequelae of SARS-CoV-2)

MODERATE

Persistent symptoms following acute COVID-19 infection, lasting weeks to months after initial recovery. Affects multiple organ systems. Estimated 10-30% of COVID-19 survivors develop long COVID. Symptoms can be debilitating and fluctuating.

Global Affected

65.0M

Countries

111

Symptoms

Fatigue
Post-exertional malaise
Shortness of breath
Cognitive dysfunction ('brain fog')
Chest pain
Palpitations
Joint pain
Muscle aches
Headache
Sleep disturbances
Loss of taste/smell
Gastrointestinal symptoms
Anxiety/depression

Treatment Options

Symptomatic management
Physical therapy/graded exercise (cautious)
Cognitive rehabilitation
Pulmonary rehabilitation
Mental health support
Sleep hygiene
Pain management
Cardiology evaluation
Autonomic dysfunction treatment

Risk Factors

1Severe acute COVID-19
2Female gender
3Age >50
4Pre-existing conditions
5Reinfection
6Viral load during acute phase
7No vaccination
8Autoimmune conditions

Diagnostic Methods

  • 1Clinical diagnosis
  • 2Exclusion of other causes
  • 3Assessment of symptoms
  • 4Functional capacity testing
  • 5Cardiopulmonary exercise testing
  • 6Brain imaging (research)
  • 7Autonomic testing

Prognosis

Variable; some recover within months, others have symptoms for years. Recovery often non-linear with relapses. Significant impact on quality of life and work capacity. New evidence suggests gradual improvement over time.

Prevention

  • COVID-19 vaccination
  • Avoiding infection
  • Early treatment of acute COVID-19
  • Public health measures

Research Status

No established cure. Vaccination reduces risk of long COVID. Paxlovid may reduce risk. Multidisciplinary rehabilitation. Antivirals studied. Low-dose naltrexone, antihistamines investigational. ME/CFS overlap recognized.

Sources

  • https://medlineplus.gov
  • https://www.mayoclinic.org
  • https://www.hematology.org/education/patients
  • https://www.ncbi.nlm.nih.gov/books
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.