DISEASE SCANNER

Global Incurable Diseases Tracker

Back to Globe
Autoimmune Disease

Chronic Inflammatory Demyelinating Polyneuropathy

MODERATE

A rare autoimmune disorder causing progressive weakness and sensory loss due to immune-mediated demyelination of peripheral nerves. Chronic counterpart to Guillain-Barré syndrome. Requires ongoing treatment to prevent progression.

Global Affected

150.0K

Countries

15

Symptoms

Progressive symmetric weakness
Numbness and tingling
Loss of reflexes
Ataxia
Fatigue
Difficulty walking
Foot drop

Treatment Options

Corticosteroids
Immunosuppressants
Biologic agents
DMARDs
Plasmapheresis
IVIG
Physical therapy
Symptom management

Risk Factors

1Female gender
2Family history
3Genetic predisposition
4Environmental triggers
5Infections
6Hormonal factors
7Smoking

Diagnostic Methods

  • 1Autoantibody testing
  • 2Inflammatory markers
  • 3Imaging
  • 4Biopsy
  • 5Clinical criteria
  • 6Exclusion of other causes

Prognosis

Variable; many autoimmune diseases are chronic with relapsing-remitting courses. Early treatment and modern biologics have significantly improved outcomes.

Prevention

  • No specific prevention
  • Smoking cessation
  • Avoidance of triggers
  • Early diagnosis and treatment
  • Regular monitoring

Research Status

IVIG, corticosteroids, and plasma exchange effective first-line. Fingolimod and other immunosuppressants in trials. Subcutaneous immunoglobulin (SCIG) for maintenance. Treatment typically lifelong.

Affected Countries

AustraliaBulgariaBrazilCanadaChinaGermanySpainFinlandFranceUnited KingdomIndiaItalyJapanMalaysiaUnited States

Sources

  • https://www.ncbi.nlm.nih.gov/books/NBK519046
  • https://www.ncbi.nlm.nih.gov/books
  • https://www.mayoclinic.org/diseases-conditions
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.