DISEASE SCANNER

Global Incurable Diseases Tracker

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Cancer

Cervical Cancer

MODERATE

Cancer that begins in the cervix, almost always caused by persistent HPV infection. One of most preventable cancers through screening and vaccination. Declining in developed countries due to screening.

Global Affected

600.0K

Countries

27

Symptoms

Abnormal vaginal bleeding
Bleeding after sex
Bleeding between periods
Menstrual bleeding longer/heavier
Unusual vaginal discharge
Pelvic pain
Pain during sex

Treatment Options

LEEP (loop electrosurgical excision)
Cone biopsy
Hysterectomy
Radical hysterectomy
Radiation therapy
Chemoradiation
Chemotherapy
Immunotherapy
Targeted therapy (bevacizumab)
Trachelectomy (fertility-sparing)

Risk Factors

1HPV infection
2Multiple sexual partners
3Early sexual activity
4Smoking
5Immunosuppression
6Long-term oral contraceptives
7Multiple full-term pregnancies
8Family history
9DES exposure (in utero)

Diagnostic Methods

  • 1Pap smear
  • 2HPV testing
  • 3Colposcopy
  • 4Cervical biopsy
  • 5Endocervical curettage
  • 6Cone biopsy
  • 7CT/MRI/PET (staging)
  • 8Cystoscopy/proctoscopy (advanced)

Prognosis

Excellent when detected early/prevented; 92% 5-year survival for localized disease. Screening and vaccination make this highly preventable. Advanced disease more challenging but still treatable. Global disparities in outcomes significant.

Prevention

  • HPV vaccination
  • Regular Pap smears/HPV testing
  • Smoking cessation
  • Safe sex practices
  • Limit sexual partners
  • Barrier contraception

Research Status

HPV vaccination dramatically reducing incidence. Screening (Pap smear, HPV testing) highly effective. LEEP and cone biopsy for precancer. Surgery, radiation, chemotherapy for invasive. Immunotherapy (pembrolizumab) for advanced.

Sources

  • https://www.cancer.org/cancer/cervical-cancer.html
  • https://www.cervicalcancer.org
  • https://www.who.int/cancer/prevention/diagnosis-screening/cervical-cancer

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.