DISEASE SCANNER

Global Incurable Diseases Tracker

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Infectious Disease

Cellulitis

MODERATE

A common bacterial skin infection affecting the deeper layers of skin and subcutaneous tissue. Usually caused by Streptococcus or Staphylococcus bacteria entering through breaks in the skin. Can spread rapidly and become life-threatening if not treated promptly.

Global Affected

14.0M

Countries

83

Symptoms

Red, swollen area of skin
Skin warmth and tenderness
Skin dimpling or orange-peel appearance
Fever and chills
Swollen lymph nodes
Red streaks extending from affected area
Blisters or skin breakdown
Fatigue and malaise

Treatment Options

Oral antibiotics (cephalexin, dicloxacillin)
MRSA-covering antibiotics (TMP-SMX, doxycycline, clindamycin)
IV antibiotics (vancomycin, daptomycin, ceftaroline)
Elevate affected limb
Warm compresses
Pain relievers (NSAIDs, acetaminophen)
Wound care and dressing changes
Hospitalization (severe cases)
Surgical drainage (if abscess present)
Treat underlying skin conditions
Prophylactic antibiotics (recurrent cases)

Risk Factors

1Breaks in skin (cuts, scrapes, burns)
2Skin conditions (eczema, psoriasis, athlete's foot)
3Diabetes
4Obesity
5Immunocompromised state
6Chronic venous insufficiency
7Lymphedema
8History of cellulitis
9Intravenous drug use
10Poor circulation
11Older age

Diagnostic Methods

  • 1Physical examination
  • 2Blood cultures (if fever present)
  • 3Wound culture (if drainage present)
  • 4Complete blood count (CBC)
  • 5Erythrocyte sedimentation rate (ESR)
  • 6C-reactive protein (CRP)
  • 7Imaging (ultrasound, CT, MRI) if deep infection suspected

Prognosis

Good with prompt antibiotic treatment. Most cases resolve within 7-10 days. Recurrence common (20-30%). Potential complications include abscess formation, sepsis, necrotizing fasciitis, and chronic lymphedema. Hospitalization required for 15-20% of cases. Mortality low (<1%) with treatment.

Prevention

  • Prompt treatment of skin injuries
  • Moisturize dry skin
  • Treat underlying skin conditions
  • Control diabetes
  • Maintain healthy weight
  • Compression stockings (if venous insufficiency)
  • Proper wound care
  • Avoid scratching insect bites
  • Regular nail care
  • Prophylactic antibiotics for frequent recurrences

Research Status

Oral antibiotics (cephalexin, dicloxacillin) first-line for uncomplicated cases. MRSA coverage (TMP-SMX, doxycycline, clindamycin) if risk factors present. IV antibiotics (vancomycin, daptomycin) for severe cases or failed oral therapy. Elevation of affected limb important. Recurrence prevention strategies for frequent cases.

Sources

  • https://www.mayoclinic.org/diseases-conditions/cellulitis
  • https://www.cdc.gov/groupastrep/diseases-public/cellulitis.html
  • https://www.hematology.org/education/patients
  • https://www.ncbi.nlm.nih.gov/books
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.