DISEASE SCANNER

Global Incurable Diseases Tracker

Back to Globe
Psychiatric Condition

Bulimia Nervosa

HIGH SEVERITY

An eating disorder characterized by recurrent episodes of binge eating followed by inappropriate compensatory behaviors to prevent weight gain, such as self-induced vomiting, laxative misuse, fasting, or excessive exercise. Affects 1-2% of women and 0.1-0.5% of men. Associated with significant medical complications.

Global Affected

64.0M

Countries

19

Symptoms

Recurrent binge eating episodes
Compensatory behaviors (vomiting, laxatives)
Preoccupation with body shape and weight
Fear of weight gain
Swollen salivary glands
Dental erosion
Electrolyte imbalances
Gastrointestinal problems
Depression and anxiety

Treatment Options

Cognitive-behavioral therapy (CBT-BN)
Interpersonal psychotherapy (IPT)
Dialectical behavior therapy (DBT)
Fluoxetine (high dose, 60mg)
Nutritional rehabilitation
Guided self-help programs
Family therapy for adolescents
Group therapy

Risk Factors

1Female gender (10:1 ratio)
2Body dissatisfaction
3Dieting and restrictive eating
4History of trauma or abuse
5Perfectionism
6Impulsivity
7Family history of eating disorders
8Participation in weight-focused sports

Diagnostic Methods

  • 1DSM-5 criteria assessment
  • 2Eating Disorder Examination
  • 3Medical evaluation for complications
  • 4Electrolyte panel
  • 5ECG
  • 6Dental examination
  • 7Assessment of binge/purge frequency
  • 8Psychiatric comorbidity screening

Prognosis

Better than anorexia nervosa. With CBT, 50% achieve abstinence from binge/purge behaviors; 30% have significant reduction. Fluoxetine reduces binge eating by 60-70%. Relapse common; 30-50% relapse within 1 year of treatment cessation. Mortality rate 2-3x general population. With treatment, 70-80% improve significantly. Chronic course possible without treatment. Medical complications often reversible with cessation of behaviors. Comorbid substance abuse worsens outcomes.

Prevention

  • Media literacy and body image programs
  • Reducing weight stigma
  • Early identification of dieting behaviors
  • Mental health screening
  • Building healthy coping skills
  • Family communication about food and weight
  • Promoting size diversity acceptance

Research Status

CBT is first-line treatment with 50% remission rates. Fluoxetine FDA-approved at high doses. Nutritional counseling important. Research on emotion regulation difficulties, dopamine reward dysfunction, and family factors. Guided self-help effective for milder cases. Treatment often outpatient unless severe complications.

Sources

  • https://www.mayoclinic.org/diseases-conditions/bulimia-nervosa
  • https://www.who.int/news-room/fact-sheets/detail/eating-disorders
  • https://www.hematology.org/education/patients
  • https://www.ncbi.nlm.nih.gov/books
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.