DISEASE SCANNER
Global Incurable Diseases Tracker
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Genetic Disorder
Beta-Thalassemia Minor (Trait)
LOW SEVERITY
Carrier state of beta-thalassemia with one normal and one mutated beta-globin gene. Mild microcytic anemia, usually asymptomatic. Important for genetic counseling as carriers can have children with thalassemia major if partner also carrier.
Global Affected
150.0M
Countries
30
Symptoms
Mild anemia
Microcytosis
Usually asymptomatic
Iron overload if incorrectly treated
Treatment Options
Genetic counseling
Supportive care
Symptom management
Enzyme replacement (if applicable)
Physical therapy
Regular monitoring
Multidisciplinary care
Risk Factors
1Family history
2Genetic mutations
3Consanguinity
4Advanced paternal age
5Ethnic predisposition
Diagnostic Methods
- 1Genetic testing
- 2Clinical evaluation
- 3Family history assessment
- 4Specialized laboratory tests
- 5Imaging studies
- 6Biopsy (if applicable)
Prognosis
Excellent. Normal life expectancy. Mild anemia well-tolerated. Important to distinguish from iron deficiency to avoid unnecessary iron loading.
Prevention
- Genetic counseling
- Carrier screening
- Prenatal diagnosis
- Preimplantation genetic diagnosis
- Family planning
Research Status
No treatment needed. Genetic counseling essential before family planning. Avoid iron supplementation unless truly iron deficient. Partner screening recommended.
Affected Countries
Sources
- https://www.ncbi.nlm.nih.gov/books/NBK1116
- https://medlineplus.gov/genetics
- https://rarediseases.org
Medical Disclaimer
This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.