DISEASE SCANNER

Global Incurable Diseases Tracker

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Cancer

Basal Cell Carcinoma

LOW SEVERITY

The most common type of skin cancer, originating from basal cells in the epidermis. Slow-growing and rarely metastasizes but can cause local tissue destruction. Strongly associated with UV exposure.

Global Affected

4.0M

Countries

22

Symptoms

Pearly or waxy bump
Flat, flesh-colored or brown scar-like lesion
Bleeding sore that doesn't heal
Raised red patch
Shiny, skin-colored bump
Pink growth with raised edges
Open sore with oozing

Treatment Options

Surgical excision
Mohs micrographic surgery
Curettage and electrodesiccation
Cryotherapy
Radiation therapy
Topical medications (imiquimod, 5-FU)
Photodynamic therapy
Targeted therapy (vismodegib, sonidegib)

Risk Factors

1UV exposure (sun, tanning beds)
2Fair skin
3Age over 50
4Family history
5Previous BCC
6Radiation therapy
7Immunosuppression
8Genetic conditions (xeroderma pigmentosum, basal cell nevus syndrome)

Diagnostic Methods

  • 1Physical examination
  • 2Dermoscopy
  • 3Skin biopsy
  • 4Shave biopsy
  • 5Punch biopsy
  • 6Excisional biopsy

Prognosis

Excellent; almost never fatal. Highly curable when treated early. Recurrence possible. Risk of second BCC increased. Regular skin exams recommended. Cosmetic outcomes generally good.

Prevention

  • Sun protection (SPF 30+)
  • Avoid tanning beds
  • Protective clothing
  • Regular skin exams
  • Early treatment of precancerous lesions

Research Status

Surgical excision and Mohs surgery highly curative. Imiquimod and 5-FU for superficial lesions. Radiation for non-surgical candidates. Hedgehog pathway inhibitors for advanced disease. Photodynamic therapy effective.

Sources

  • https://www.aad.org/public/diseases/skin-cancer/types/common/bcc
  • https://www.cancer.org/cancer/basal-and-squamous-cell-skin-cancer.html
  • https://www.skincancer.org/skin-cancer-information/basal-cell-carcinoma
  • https://www.cancer.gov/

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.