DISEASE SCANNER

Global Incurable Diseases Tracker

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Dermatologic Condition

Actinic Keratosis (Solar Keratosis)

LOW SEVERITY

Rough, scaly patches on the skin caused by damage from the sun's ultraviolet (UV) rays. Considered precancerous lesions that can develop into squamous cell carcinoma. Most common on sun-exposed areas.

Global Affected

60.0M

Countries

22

Symptoms

Rough, dry, scaly patch
Flat or slightly raised
Red, pink, or skin-colored
May itch or burn
Bleeding
Tender to touch
Multiple lesions common

Treatment Options

Cryotherapy
Topical 5-fluorouracil
Topical imiquimod
Topical diclofenac
Photodynamic therapy
Curettage
Laser therapy
Ingenol mebutate
Regular monitoring

Risk Factors

1Sun exposure
2Fair skin
3Age (over 40)
4Outdoor occupation
5History of sunburns
6Weakened immune system
7Prior PUVA therapy

Diagnostic Methods

  • 1Visual examination
  • 2Dermoscopy
  • 3Skin biopsy (if suspicious)
  • 4Palpation (rough texture)

Prognosis

Good; most treatable. Risk of progression to SCC (approximately 10% over 10 years). Regular monitoring important. Field cancerization concept important for treatment planning.

Prevention

  • Sun protection (SPF 30+)
  • Avoid tanning beds
  • Protective clothing
  • Regular skin exams
  • Early treatment of lesions

Research Status

Cryotherapy most common treatment. Topical 5-FU, imiquimod, and diclofenac effective for field treatment. Photodynamic therapy for multiple lesions. Ingenol mebutate short treatment course. Regular surveillance important due to SCC risk.

Affected Countries

United StatesUnited KingdomCanadaAustraliaNew ZealandGermanyFranceItalySpainJapanBrazilMexicoAustraliaNew ZealandSwedenNorwayFinlandDenmarkNetherlandsBelgiumSwitzerlandAustria

Sources

  • https://www.skincancer.org/skin-cancer-information/actinic-keratosis
  • https://www.mayoclinic.org/diseases-conditions/actinic-keratosis
  • https://www.hematology.org/education/patients
  • https://www.ncbi.nlm.nih.gov/books
  • https://rarediseases.org/rare-diseases

Medical Disclaimer

This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.