DISEASE SCANNER
Global Incurable Diseases Tracker
Achalasia
A rare esophageal motility disorder where the lower esophageal sphincter fails to relax and the esophagus lacks normal peristalsis. Causes difficulty swallowing and regurgitation. Degeneration of nerve cells in esophagus.
1.5M
19
Symptoms
Treatment Options
Risk Factors
Diagnostic Methods
- 1Barium swallow (bird's beak appearance)
- 2Esophageal manometry
- 3Upper endoscopy
- 4CT scan (rule out pseudoachalasia)
- 5Timed barium swallow
Prognosis
Treatable but not curable. Treatments improve symptoms but esophageal function remains abnormal. May require repeat treatments. Risk of esophageal cancer increased (surveillance recommended). Quality of life significantly improved with treatment.
Prevention
- No known prevention
- Early diagnosis and treatment
- Regular surveillance for esophageal cancer
- Manage reflux symptoms
Research Status
Pneumatic dilation and Heller myotomy most effective treatments. POEM (peroral endoscopic myotomy) increasingly popular minimally invasive option. Botulinum toxin for poor surgical candidates. Calcium channel blockers and nitrates provide temporary relief.
Affected Countries
Sources
- https://www.mayoclinic.org/diseases-conditions/achalasia
- https://www.ncbi.nlm.nih.gov/books
- https://www.mayoclinic.org/diseases-conditions
- https://www.crohnscolitisfoundation.org
Medical Disclaimer
This information is for educational purposes only. Always consult healthcare professionals for medical advice, diagnosis, and treatment.